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Berdazimer Topical Gel (Zelsuvmi)
The U.S. Food and Drug Administration has approved the first and only prescription drug for the home treatment of molluscum contagiosum. Berdazimer, administered with a hydrogel, is a nitric oxide-releasing agent with antiviral properties.
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Improve Screening and Retesting for Trichomoniasis
Infection by the protozoan Trichomonas vaginalis is the most common nonviral sexually transmitted infection, with an estimated 6.8 million cases in the United States annually. It can go undiagnosed because most infected people (up to three out of four) do not experience symptoms. Left undiagnosed and untreated, trichomoniasis can increase the risk of pelvic inflammatory disease, infertility, and acquiring HIV and other STIs.
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Safety and Tolerability of Inclisiran
A pooled analysis of seven relatively short-term ORION studies of inclisiran vs. placebo for lowering low-density lipoprotein cholesterol that assessed safety and tolerability for up to six years showed that inclisiran has similar rates of adverse events, excluding injection site reactions, as placebo treatment and is associated with fewer major adverse cardiovascular events.
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National Screening Guidelines for Chlamydia
Reproductive and sexual health providers could reference evidence-based national guidelines for chlamydia screening and care, including guidelines from the U.S. Preventive Services Task Force, the Centers for Disease Control and Prevention, and the American Academy of Family Physicians.
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A Comparison of Acute Migraine Therapies Using Big Data
In a big data-driven observational study that compared 3 million treated migraine attacks captured from a migraine diary smartphone app, triptans were found to be the most efficacious treatment class. Among the triptans, eletriptan had the highest rate of success. Consistent with clinical practice and recent consensus statements, the success of triptans was followed by ergots and antiemetics.
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Best Practices Needed in Screening and Treating Chlamydia
Chlamydia infection affects more than 1.7 million people each year, making it the most common bacterial STI. Using a screening tool and checklist, a family planning clinic found success in improving the chlamydia screening rate, identifying more cases of the STI, and making patient visits more efficient by reducing time spent on visits.
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New Study Shows Oral Contraceptives Decrease Risk of Hypothyroidism
When researchers decided to explore the link between hormonal birth control and the risk of hypothyroidism, they made a surprising discovery: Contrary to earlier evidence, hormonal contraception decreases the risk of developing hypothyroidism.
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Nitrates in Food Reduce Cardiovascular Risk
Dietary nitrates, such as in beetroot juice, improve the cardiovascular risk profile, lowering blood pressure and enhancing endothelial function.
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Mental Health Screening Needed for Optimal Contraceptive Counseling
Mental health conditions are common among people of reproductive age. Still, both physicians and patients may have misconceptions about using hormonal contraception if patients are diagnosed with depression or other mental health issues. New research suggests that barriers to effective contraceptive use should be addressed, and clinicians need to dispel myths about the negative psychiatric impacts of hormonal contraceptives.
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Is Brain Impairment Following COVID-19 Hospitalization Worse Than for Other Severe Illnesses?
The authors of this prospective cohort study with matched controls found that long-term brain health following severe COVID-19 hospitalization was impaired but was similar to hospitalization from other severe diseases.